Fig. 1: Over-expression of SM TFs lead to the production of diverse metabolites. | Communications Biology

Fig. 1: Over-expression of SM TFs lead to the production of diverse metabolites.

From: Systematic over-expression of secondary metabolism transcription factors to reveal the pharmaceutical potential of Aspergillus nidulans

Fig. 1

a Western blot analysis of AflRHA (MW = 51.3 kD) and AN6790FLAG (MW = 71.7 kD) in the respective over-expression (OE) strains grown in the presence (+) and absence (-) of the xylose inducer. The expected protein size is indicated; b Images of fermentation broth (top panel) and their EtoAc extracts (bottom panel) of the indicated over-expression strains grown with 1% xylose induction; c, d LC-MS profiles of the EtoAc extract from the wild-type and AflR over-expression strains with 1% xylose induction; e Images of fermentation broth (top panel) and their ethyl acetate (EtOAc) extracts (bottom panel) of the indicated over-expression strains grown with 1% xylose induction.

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