Fig. 7: Spatial transcriptomic profiles of kidneys from three groups of LN mice. | Communications Biology

Fig. 7: Spatial transcriptomic profiles of kidneys from three groups of LN mice.

From: Cxcl9high macrophages recruit circulating Cxcr3+ plasmablasts into kidneys to promote pathogenesis of lupus nephritis mice

Fig. 7

A UMAP visualization of 11,505 spots in the kidney of LN. B UMAP visualization of cell subgroups in the kidneys of LN. C Representative genes used for annotating spatial transcriptomic cell maps in the kidneys of LN, along with the corresponding gene expression levels of immune cells in each cell subgroup. D H&E staining profiles and corresponding spatial transcriptome profiles of the kidneys of LN, with small black arrows indicating the distribution of immune cells in the kidneys. Glomerulus (GLO), Proximal Tubule (PT), Loop of Henle (LOH), Distal Tubule/Connecting Tubule/Collecting Duct (DT/CNT/CD), Transitional Epithelium (TE), Artery/Immune Cell (ART/IC), Immune Cell (IC), and Adipose Tissue (AT).

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