Fig. 5: Receptor binding inhibition screening against five long-chain α-neurotoxins.

The ability of VHH clones to prevent long-chain α-neurotoxins from binding to the human acetylcholine receptor was assessed with a DELFIA. An isotype control VHH that was specific to cytotoxins was included as a negative control. The vertical red dotted line indicates a 1:1 molar ratio of VHH:toxin.