Fig. 6: Assessment of VHHs capability of neutralising the cell depolarisation caused by long-chain α-neurotoxins in vitro. | Communications Chemistry

Fig. 6: Assessment of VHHs capability of neutralising the cell depolarisation caused by long-chain α-neurotoxins in vitro.

From: Structural mechanisms behind the neutralisation of long-chain α-neurotoxins by broadly neutralising VHHs discovered using a consensus antigen

Fig. 6

The VHHs were preincubated with different long-chain α-neurotoxins at molar ratios ranging from 1:9 to 9:1 (3:1 for αBgtx) VHH:toxin. The resulting normalised peak current is shown. Toxins were used at concentrations ranging between IC10 and IC90, as indicated by the peak current obtained in the absence of VHH.

Back to article page