Fig. 4: Comparison of structural similarity between molecular fingerprints and SICL.

a Comparison of average Tanimoto similarity scores and SICL across molecular formula groups. SICL_Norm represents SICL values normalized by the maximum, while SICL_Norm_pairwise denotes pairwise similarity scores calculated from normalized SICL values within each formula group. b Distribution of pairwise similarity scores for each molecular formula group (box plots).