Fig. 6: Functional driver genes contributed to proliferation and colony formation in liver cancer cell line Huh7.
From: Causal network inference based on cross-validation predictability
a Colony formation of. Huh7 cells after knocked out the top ten functional driver genes. b The statistical analysis of colonyformation, n = 5 independent experiments, t-test. c, e were performed in Huh7 cels knocked out SNRNP200, XRN2. RALGAPB andSRSF10 genes. c BrdU assay of these cells by flow cytometer, d The statistical amalysis of BrdU assay. n = 3 independent experiments, t-test. e Cells were stained with anti-Ki67 antibodies (green) and DAPI to visualizeDNA (blue), Ki67 presents (green) and DAPI to visualize DNA (blue), Scale bars: 100 um. f The statistical analysis ofKi67 staining. n-5independent experiments, t-test.
