Extended Data Fig. 4: Lipid content in SRR-KO cells rescued by pyruvate or acetate supplementation.
From: Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine
a. Lipid droplet content assessed by Nile red staining in EV and SRR-KO DLD-1 and HCT116 cells after incubation with 1 mM pyruvate, 5 mM acetate or vehicle (DDW) for 72 hours, and WiDr cells stably expressing SRR-GFP or GFP. Nuclei (blue), lipid droplet (red). Images are representative of n = 3 biologically independent experiments.
