Extended Data Fig. 8: The mRNA expression levels of genes related glycolysis and serine dehydratase.
From: Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine
a. Representative glycolytic pathway. b. Heat map of RNA-seq data related to glycolytic pathway in EV and SRR-KO cells of DLD-1 and HCT116 cells. c. FPKM of serine racemase and serine dehydratase in EV cells of DLD-1 and HCT116 cells, derived from RNA-seq data. d. Serine dehydratase mRNA expression in non-neoplastic and tumor of colorectal tissue from the ONCOMINE datasets. n = 22 non-neoplastic mucosa and n = 183 adenocarcinoma in the TCGA dataset, and n = 10 non-neoplastic mucosa and n = 5 adenoma in Skrzypczak’s dataset. P-values were determined by two-tailed Mann–Whitney U-test.
