Extended Data Fig. 1: SRR protein expression levels in colorectal carcinoma cases.
From: Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine
a. Representative images of two independent experiments of immunohistochemistry of SRR in colorectal carcinoma tissues with high (score 2) and low (score 1) signal intensity, which were used to calculate H-scores. Scale bars, 200 μm. b. SRR protein expression levels in 83 colorectal carcinoma cases according to tumor progression (T grade), the degree of lymph node metastasis (N grade), or the existence of other organ metastasis (M grade) were evaluated by calculating H-scores. The number of cases were T1 (n = 12), T2 (n = 13), T3 (n = 47), T4 (n = 11), N0 (n = 45), N1/2/3 (n = 38), M0 (n = 66) and M1 (n = 17). The middle line indicates the mean, and the top and bottom line indicate standard deviation. P-values were determined by two-tailed Mann–Whitney U-test.
