Extended Data Fig. 7: Expression profile of expressed non-coding RNAs against chronological age.

a, The heatmap of expressed lncRNAs (FPKM > 2) significantly related to chronological age (FDR < 0.1). The samples (columns) were sorted by age and lncRNAs were sorted by PCC of expression to age from high to low. b, The heatmap of expressed circRNAs (TPM > 2) significantly related to chronological age (FDR < 0.1). The samples (columns) were sorted by age and circRNAs were sorted by PCC of expression to age from high to low. c, Top three enriched terms for parent genes of age-up (top) and age-down circRNAs. P values are derived from hypergeometric test (Methods). d, The correlation between age and total expression level of circRNAs. P value is derived from two-sided t test.