Extended Data Fig. 2: Glycolysis enzymes and intermediates in cMPC1-/- hearts.
From: Mitochondrial pyruvate carriers are required for myocardial stress adaptation
a, Glycolysis-derived metabolic intermediates in 8-week-old control and cMPC1-/- hearts were determined by GC-MS. Mice were random fed before sacrifice. (Control, 15; cMPC1-/-, 11). b, hexokinase I (HK I), GAPDH, O-GlcNAc transferase (OGT) and glycogen synthase (GS) blots were performed in lysates of cardiomyocytes isolated from 8-week-old control and cMPC1-/- mice. Protein quantification was normalized to total Coomassie blue staining. (n = 5 both groups). Data are presented as mean ± SEM and analyzed by two-tailed unpaired Student’s t-test.
