Extended Data Fig. 5: The core circadian-clock is not zonated. | Nature Metabolism

Extended Data Fig. 5: The core circadian-clock is not zonated.

From: Space-time logic of liver gene expression at sub-lobular scale

Extended Data Fig. 5

a, Spatial and temporal profiles and fits for circadian core-clock genes. Peak times are indicated on the temporal representation. For the genes Cry1 and Clock, additional dashed lines represent fits for the R model, as the Schwartz BIC weights from the R and Z+R models were close (Supplementary Table 2). b, Amplitudes and peak times of the core-clock circadian genes in a polar coordinate representation (clock-wise ZT times are indicated, distance from the center corresponds to the amplitude) show the expected organization of core clock transcript in the liver.

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