Extended Data Fig. 4: DNA damage therapy induces ROS in breast cancer cells. | Nature Metabolism

Extended Data Fig. 4: DNA damage therapy induces ROS in breast cancer cells.

From: NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

Extended Data Fig. 4

a, DCFDA staining showing ROS levels in T47D, BT474, and MCF7 cells treated with 1 μM fulvestrant for 48 hours. Data are representative of n = 3 biologically independent replicates for a single experiment. Significance was determined by two-sided Student’s t test. b, DCFDA staining showing ROS levels in MCF7, SKBR3, MDA-MB-231, BT474, and T47D cells treated with indicated doses of etoposide for 48 hours. Data are representative of n = 3 biologically independent replicates for a single experiment. Significance was determined by two-sided Student’s t test.

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