Extended Data Fig. 3: Maternal exercise alters expression of cardiac genes. | Nature Metabolism

Extended Data Fig. 3: Maternal exercise alters expression of cardiac genes.

From: Exercise-induced 3′-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring

Extended Data Fig. 3

Expression of cardiac genes involved in (a,b) mitochondrial activity, (c,d) fibrosis, and (e,f) fetal reprogramming and male and female offspring from WT and 3’SL-/- mice. Data are expressed as the mean ± SEM (for males, WT Sed n=9, WT Train n=9, 3’SL-/- Sed n=6, 3’SL-/- Train n=5 for Figure a; WT Sed n=9, WT Train n=5, 3’SL-/- Sed n=6, 3’SL-/- Train n=5 for Figures c, e. For females, WT Sed n=9, WT Train n=10, 3’SL-/- Sed n=4, 3’SL-/- Train n=4 for Figures b, d; WT Sed n=9, WT Train n=4, 3’SL-/- Sed n=4, 3’SL-/- Train n=4 for Figure f). Asterisks represent differences compared to Sedentary offspring of the same gender (*P < 0.05; **P < 0.01) or compared to 3’SL-/- Sedentary offspring (#P<0.05). One-way ANOVA was used for a-f with Tukey’s multiple comparisons tests.

Back to article page