Extended Data Fig. 4: Expression of THZ1-rescued genes in ADPKD mouse kidneys. | Nature Metabolism

Extended Data Fig. 4: Expression of THZ1-rescued genes in ADPKD mouse kidneys.

From: Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease

Extended Data Fig. 4

qRT-PCR analysis of THZ1 downregulated (a) and upregulated (b) genes mRNA level in THZ1 treated mouse kidney tissues (n = 3 biologically independent mice per group). Data are represented as means ± s.e.m., analysed by unpaired two-sided Student’s t-test, Sh3rf2 *P = 0.0127, Adamts5 **P = 0.0053, Arhgef2 ****P < 0.0001, Sh3bp2 **P = 0.0096, Mdh1 **P = 0.0071, Fdxr **P = 0.0038, Csrp2 ***P = 0.0006, Aldh9a1 **P = 0.0098.

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