Extended Data Fig. 3: Glis1 suppressed somatic state genes during somatic cell reprogramming.
From: Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade
a, The binding of Glis1 on glycolytic process gene loci was determined by ChIP–qPCR. TF-NC represents negative control. Data are presented as the mean ± S.D. (n = 3, each group).Group differences are analyzed by the two-tailed Student’s t test. b, Time courses of qPCR analyses of somatic state gene expression levels by SKO plus Flag and SKO plus Glis1. Data are presented as the mean ± S.D. (Setbp1, Col11a1 n=3; other genes, n=4 each group).Group differences are analyzed by the two-tailed Student’s t test. c, RT-qPCR analysis for detecting the glycolysis genes knockdown efficiency in MEFs.
