Extended Data Fig. 7: Table of Spearman correlation coefficients and Beta-coefficients testing associations between age and uniqueness in the MrOS cohort.

Uniqueness measures reported in this table were calculated at the genus level. ‘Health Stratification’ corresponds to the metric used to define healthy individuals. ‘ Spearman Rho’ reports the Spearman correlation coefficient between age and microbiome uniqueness for the specified group of participants, while the ‘pvalue’ column provides the corresponding p-value. ‘Beta_coeff’ is the BMI adjusted age beta-coefficient predicting uniqueness across the same stratifications as the ‘Spearman Rho’ column. ‘Coef_pvalue’ provides the p-value corresponding to the age Beta-coefficient from linear regression models. ‘Sample_size’ is the number of participants in each stratification while the last column ‘Healthy (yes = 1/no=0)’ specifies whether the group of participants is the healthy subgroup (yes(1)), or the remainder of the cohort (No(0)). Significant p-values (P < 0.05, two-sided) are highlighted in red. No multiple hypothesis correction was performed.