Extended Data Fig. 6: Additional DVC neuronal populations with previously-defined functions. | Nature Metabolism

Extended Data Fig. 6: Additional DVC neuronal populations with previously-defined functions.

From: A genetic map of the mouse dorsal vagal complex and its role in obesity

Extended Data Fig. 6

Expression of genes defining DVC neurons previously implicated in metabolic control. Top, expression specificity (ESμ) of selected genes. Bottom, the most likely DVC origin of the neuronal populations. Mc4r cholinergic (Chat3) DMV neurons regulate circulating insulin39, Hsd11b2 and Nr3c2 glutamatergic (Glu2) NTS neurons drive sodium appetite40 and Lepr and Gal glutamatergic (Glu3) NTS neurons module breathing41. Data for reconstruction of figure are available in Supplementary Data 2.

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