Extended Data Fig. 8: GDF15 increases sympathetic tone.
From: TFEB–GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response
a-b, Action potential (AP) firing number under various stimulus intensity (a), and relationship between AP firing number and stimulus intensity (b) in mice treated with vehicle (Veh) or GDF15. c-d, Voltage tracing under various stimulus intensity (c), and AP threshold stimuli (d) in mice treated with vehicle or GDF15 (n=6). All data are shown as means ± SEM. **P < 0.01 and ***P < 0.001 by two-tailed Student’s t-test.
