Extended Data Fig. 5: Indirect calorimetry of IRΔTan-mice.

a. Respiratory exchange ratio (RER) during day and night, p(Day) = 0.0448, unpaired, two-tailed Student’s t-test. b. Energy expenditure (EE) measurement during day and night. c. Mean locomotor activity during day and night. d. O2 consumption. e. CO2 production. a-e. n = 13/ IRGFP-Tan; n = 14/ IRΔTan. Data are represented as the mean ± SEM.