Extended Data Fig. 1: GP73 secretion is induced from multiple tissues upon fasting.
From: GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia
a-b, Intracellular GP73 (a) or supernatant GP73 levels (b) in HepG2 cells transfected with different concentrations of Flag-GP73. Cell-based studies were performed independently at least three times with comparable results. P = 0.0327 for 0.025 μg versus 0 μg, P < 0.0001 for 0.1 μg versus 0 μg, 0.4 μg versus 0 μg and 1.6 μg versus 0 μg by one-way ANOVA followed by Bonferroni’s post hoc test. Cell-based studies were performed independently at least three times with comparable results. The data were the means ± SEMs. *P < 0.05, ***P < 0.001.
