Extended Data Fig. 6: snRNA-seq of ingWAT in mice with HFD and pAAV-CAG-GFP or pAAV-CAG-Rspo2 AAV.
From: Identification of a regulatory pathway inhibiting adipogenesis via RSPO2
a) Feature plot for the origin of pAAV-CAG-GFP or pAAV-CAG-Rspo2 conditions. b) Feature plot for the number of genes expressed in each nucleus. c) Feature plots for adipocyte markers Adipoq, Lep, Plin1, and Adrb3. d) Heat map of signature genes for each population. e–g) Scatter plots for gene expression analysis between pAAV-CAG-GFP and pAAV-CAG-Rspo2 within adipocytes (e), macrophages-1 (f), and macrophages-2 (g). h) Heat map of signature genes for preadipocytes population PA-2-PA-5. i) Feature plots for Ctnnb1 in preadipocytes clusters in pAAV-CAG-GFP and pAAV-CAG-Rspo2 ingWAT, separated by conditions. j) Feature plots for Dpp4, Pparg, Fmo2 in preadipocytes clusters in pAAV-CAG-GFP and pAAV-CAG-Rspo2 ingWAT. k) Dot plots for representative markers of each cluster PA1-PA-5, separated by conditions. l) Scatter plots for gene expression analysis between pAAV-CAG-GFP and pAAV-CAG-Rspo2 within PA-1-PA-5. This figure is related to Fig. 7.
