Extended Data Fig. 10: Analysis of WT and MUT S4 graft sections.
From: Abnormal exocrine–endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8
Representative immunostaining images of grafts derived from mutant (n = 4) or wild-type (n = 4) S4 cells stained for β-cell markers such as INS in green, PDX1, NKX2.2, NeuroD1, and NKX6.1 in red. Human foetal pancreas (34 weeks, n = 1 donor) was used as control. Donor information is given in Supplementary Table 1. Nuclei stained with DAPI (blue). Scale bar is 20 μm.
