Extended Data Fig. 7: CCL18-induced upregulation of transcription factors. | Nature Metabolism

Extended Data Fig. 7: CCL18-induced upregulation of transcription factors.

From: The transcription factor RFX5 coordinates antigen-presenting function and resistance to nutrient stress in synovial macrophages

Extended Data Fig. 7

MDM from healthy individuals and RA patients were induced with M-CSF over 6 days and differentiated with LPS/IFN-γ. Color scales are presented by fold change. a, Gene expression profiling for 20 transcription factors in Mϕ treated with rhCCL18 (50 ng/mL, n = 5) or vehicle (n = 5) for 48 h. Transcripts were quantified by RT-PCR. b, Gene expression of 20 transcription factors in Mϕ generated from controls and RA patients. mRNA expression was measured by RT-PCR.

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