Extended Data Fig. 8: Solar exposure induces ghrelin and hunger in humans, Related to Fig. 7.
From: Food-seeking behavior is triggered by skin ultraviolet exposure in males
a, Dot plot representing the solar UVB radiation dose (measured in mW/cm2), measured using the UVX radiometer at indicated times of the day in summer (August) and winter (December) months. Data are presented as mean ± SEM for each time point of the day (n = 4 separate days of measurement). b, Graphical summary presents the discovery of UVB as a novel food-seeking behavior trigger, in which men and women have a different eating physiology and in which several extrinsic as well as intrinsic factors can affect this behavior, including sex-specific steroids like estrogen and testosterone. The sex-based disparity in ghrelin levels following the UVB exposure are reflected in the food-seeking behavior and hunger, as we observed in several experimental models, that is, mouse experiments, human cohort study and human questionnaire.
