Fig. 8: Strength of association of selected predictors for senescence markers and GREM1 and BMP4 mRNA levels in patients with NAFLD/NASH. | Nature Metabolism

Fig. 8: Strength of association of selected predictors for senescence markers and GREM1 and BMP4 mRNA levels in patients with NAFLD/NASH.

From: BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH

Fig. 8

a–e, Relative feature importance for senescence markers and GREM1 and BMP4 mRNA, using conditional random forest and gradient boosting model diagnostics, is presented in each panel. Predictors that display a pronounced increased in importance compared with other predictors are strong predictors for the outcome. Partial dependence plots are included to display interaction effects between features with strong predictability for the outcome.

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