Extended Data Fig. 8: Metabolic analyses of Mac-MitoNEETTG mice. | Nature Metabolism

Extended Data Fig. 8: Metabolic analyses of Mac-MitoNEETTG mice.

From: Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations

Extended Data Fig. 8

(a-e) Six-week-old male control and Mac-MitoNEETTG mice were fed HFD for 20 weeks and then switched to HFD dox for 1 week. Metabolic analyses were performed at 3 d before and 7 d after diet change (n = 6). (a) Experimental design. (b) Body weight (n = 5). (c) Hourly food intake (n = 6). (d) Respiratory exchange ratio (n = 6). (e) Energy balance (n = 6). Significance in (b-e) between control and Mac-MitoNEETTG was calculated using a 2-way ANOVA with Sidak’s post-test for multiple comparisons. Error bars represent mean ± S.E.M. * (P < 0.05), ** (p < 0.01), *** (p < 0.0001), **** (p < 0.00001).

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