Extended Data Fig. 4: Knockdown of NPFR in the fat body leads to increased food intake after starvation, reduced starvation resistance, and lower glycogen stores.
From: A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila
(a) Food intake measured by dye assay (medium containing 9% sugar and 8% yeast); n = 8 Cg > , n = 10 Cg > NPFRiTRiP. (b) Survival during starvation (n = 100 Cg > , n = 50 Cg > NPFRiTRiP). (c) Glycogen levels in fed and 15-hour-starved females; all n = 10. All animals were mated females. Bars represent mean±SEM. ns, non-significant. a, c: Two-tailed unpaired Student’s t test. b: Gehan-Breslow-Wilcoxon test.
