Extended Data Fig. 10: Analyses of mitochondrial membrane potential and ROS levels in Hk2fl/fl and Hk2-deficient microglia upon LPS/ poly(I:C) stimulation. | Nature Metabolism

Extended Data Fig. 10: Analyses of mitochondrial membrane potential and ROS levels in Hk2fl/fl and Hk2-deficient microglia upon LPS/ poly(I:C) stimulation.

From: Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity

Extended Data Fig. 10

(a-d) Analysis of microglial mitochondrial membrane potential and mitochondrial ROS after stimulation of LPS or poly(I:C) from Hk2fl/fl and Hk2-cKO mice in the presence or absence of Mito-TEPMO. n = 6 or 7 (a), 7 or 6 (b), 7 or 5 (c), 6 or 6(d) independent cultures for each treatment in Hk2fl/fl or Hk2-cKO groups, respectively. Data are presented as means ± SEM. Two-way ANOVA followed by Bonferroni’s post hoc tests for a-d, *p < 0.05, **p < 0.01 and ***p < 0.001.

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