Extended Data Fig. 6: Characterization of subanterior rectus sheath hPSC-islet grafts in Monkey 6-8 at 13 wpt.

a-f, Representative immunofluorescence staining of islet hormones, pancreatic transcription factors (PDX1, NKX6.1, NKX2.2 and MAFA) and UCN3 in subanterior rectus sheath grafts. Scale bar, 50 μm. Similar results were obtained from five independent grafts. g, Representative immunohistochemical staining of endothelial marker CD31 in subanterior rectus sheath grafts. Scale bars, 100 μm; for the enlarged view (indicated with green border), 25 μm. Similar results were obtained from five independent grafts.