Extended Data Fig. 4: Evaluation of hPSC-islet grafts in Monkey 3 and 4 at 4 weeks post-transplantation. | Nature Metabolism

Extended Data Fig. 4: Evaluation of hPSC-islet grafts in Monkey 3 and 4 at 4 weeks post-transplantation.

From: Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets

Extended Data Fig. 4

a, Representative immunofluorescence staining of pancreatic transcription factors (TFs) and UCN3 in subanterior rectus sheath grafts in Monkey 4. Scale bar, 50 μm. Similar results were obtained from five independent grafts. b, Representative immunohistochemical staining of T cell marker CD3, B cell marker CD20 and macrophage marker CD68 in subanterior rectus sheath grafts (left). Monkey spleen or liver sections were used as control. The quantitative analysis of immunological infiltration in hPSC-islet grafts (n = 10 independent grafts) (right). Data presented as mean ± SEM. Scale bars, 100 μm.

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