Extended Data Fig. 4: EVs derived from S.Tm-infected BMDM decreased iron level and bacterial number in blood.
From: Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
a,b, The infected BMDM-derived EVs [BMDM(S.Tm)-EVs group] and infected BMDM-derived EVs pretreated with excess holo-transferrin [BMDM(S.Tm)-EVs+holo-Tf group] were injected into GW4869-pretreated infected mice respectively. a, The iron level in serum. n = 4 mice. b, Viable count of S.Tm in blood. n = 4 mice. For a,b, data are represented as the mean ± s.d. For a,b, statistical significance was assessed by one-way ANOVA with Tukey’s post-hoc test.
