Extended Data Fig. 8: Generation of Wdr24S155D and Wdr24S155A knock-in mice by CRISPR-Cas9-mediated genome editing. | Nature Metabolism

Extended Data Fig. 8: Generation of Wdr24S155D and Wdr24S155A knock-in mice by CRISPR-Cas9-mediated genome editing.

From: AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Extended Data Fig. 8

a, sgRNA sequence and part of ssODN sequence used for generating Wdr24S155A/D knock-in mice. b, Sanger sequencing results of hetero Wdr24S155D knock-in mouse genomic DNA. c, Sanger sequencing results of hetero Wdr24S155A knock-in mouse genomic DNA. d, Neonates from WDR24+/A parents were counted at birth.

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