Extended Data Fig. 4: GIP and amino acids synergistically increase glucose secretion in human islets.
From: The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets

Human islets were treated with 30 nM hGIP or 3 mM amino acids (combination of glutamine, arginine, alanine, and leucine), individually or in combination. All values are mean ± SEM, n = 3/group. A two-way ANOVA with Tukey’s posthoc test was used.