Table 2 Datasets used for validation, not part of the atlas. For detailed sample information, including sex, please refer to Supplementary Table 12
From: Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas
Species | Description | N samples | Technology | N cells (N β-cells) | GEO accession | Reference |
|---|---|---|---|---|---|---|
Mouse | Healthy adult and aged islets | 2 | SMARTer | 207 (207) | ||
Mouse | Endocrine cells from healthy young and adult mice and adult mice treated with STZ or STZ and insulin, with samples collected at different times after STZ treatment | 17 | STRT-seq | 2,999 (1,005) | ||
Human | Islets from non-diabetic, T1D and non-diabetic islet autoantibody positive donors, including child donors | 24 | Chromium v2/v3 | 66,052 (11,298) | ||
Human | Islets from non-diabetic and T2D adult donors | 18 | SMARTer Ultra Low RNA | 1,600 (503) | ||
Human | Islets from non-diabetic adult and aged donors | 5 | Chromium v2 | 26,474 (11,923) | ||
Human | Islets from non-diabetic child and adult donors | 8 | Smart-seq2 | 2,282 (348) | ||
Human | Islets from adult non-diabetic and T2D donors | 8 | SMARTer | 617 (264) | ||
Human | FACS-sorted islet cells from adult and aged donors with or without T2D | 14 | Smart-seq2 | 2,245 (674) | GSE124742 (FACS) | |
Human | Patch-seq of islet cells from adult and aged donors without diabetes, with T1D (adult only) or with T2D | 53 | Smart-seq2 | 2,319 (496) | ||
Human | Islets from non-diabetic and T2D adult donors | 9 | Drop-seq | 27,996 (9,958) | ||
Human | Islets from non-diabetic child and non-diabetic and T2D adult donors | 22 | Smart-seq | 619 (182) | ||
Human | Islets from non-diabetic child and non-diabetic, T1D and T2D adult donors | 9 | Smart-seq | 457 (111) |
