Extended Data Fig. 2: D5-Phe metabolite study.
From: Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial
The LS mean change from baseline Day −1 in D5 Phe metabolites was determined at day 14 for SYNB1618, (navy; n = 10) and SYNB1934 (orange; n = 5). A. Plasma D5 TCA AUC change from baseline in LS mean AUC 0–24 µM*h. B. Urinary D5 HA change from baseline in amount excreted (AeT) in mmol over 6 hours.
