Extended Data Fig. 1: Proteome analysis of liver and muscle of whole body inceptor KO vs. WT mice. | Nature Metabolism

Extended Data Fig. 1: Proteome analysis of liver and muscle of whole body inceptor KO vs. WT mice.

From: Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity

Extended Data Fig. 1

Principle component analysis (PCA) of all tissue samples (a). Clustering of quadriceps muscle (left), liver (middle) and hypothalamus (right) samples as well as z-scored protein intensities. Bar beneath the clustering indicates genotype (WT: white, KO: red) (n = 3 each genotype for liver, n = 3 WT, n = 2 KO for muscle) (b). Volcano plots of the same organs as in (b) ProteinGroups only found in one condition are indicated in black (c) (n = 3 each genotype for liver, n = 3 WT, n = 2 KO for muscle).

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