Extended Data Fig. 9: Basic learning and memory is similar in wildtype and PTG−/− mice in the Morris Water Maze (MWM) test.

(a, b) Latency to escape from swimming in the water and to reach a platform (a) and average distance traveled until the platform was reached (b) during the training period in the Morris Water Maze (MWM) of wildtype (WT) and gPTG−/− mice. N = 8 mice per group; Two-way ANOVA with Bonferroni post hoc test. (c, d) Latency to first entry the platform area (c) and percent of time WT and gPTG−/− spent in the quadrant of the platform (d) during the last test of the MWM (8 days after start of training) when the platform has been removed. No differences in learning and memory where observed. Unpaired two-tailed t-test; N = 8 mice per group; Data represent mean ± s.e.m.