Extended Data Fig. 5: A cellular map of human preadipocytes and adipocytes.
(a) Boxplot showing the number of quantified proteins per organelle fraction in adipocytes and preadipocytes (n = 7, error bars spread from min to max, box extends from the 25th to 75th percentile, line represents the median). (b) UMAP visualization of adipocyte PCP dataset. Proteins are coloured according to their organelles. Names of canonical markers are indicated. (c) The number of organelle markers per compartment and prediction accuracy of these markers by SVMs for preadipocytes (pAd) and mature adipocytes (mAd). (d) Number of proteins with single- and dual-protein predictions in the preadipocytes and adipocytes. (e) Circular plots of the first and second organelle predictions for preadipocyte and adipocyte organelle maps. Each Circos plot depicts the location of the first organelle in the outer ring and the second organelle in the inner ring. The second organelle is indicated in colour. Each connection line displays a combination of dual localizations, as revealed by the organelle map. The colour of the connection line corresponds to the first organelle assignment.
