Extended Data Fig. 8: Representative images of MASLD histopathology features in the OB-GAN-C2-12W model.

a. Panlobular distribution of steatosis, grade 3, H&E stain, x50; b. Necroinflammatory focus (arrowhead), H&E stain, x200; c. Ballooned hepatocyte (arrow), H&E stain, x200; d. Periportal and perisinusoidal fibrosis, stage 2, Sirius red stain, x50 (THV terminal hepatic venule, PT portal tract).