Extended Data Fig. 1: Representative Z-spectra (a-c), CrCEST (d), and CrCEST maps (e) under CL 316, 243 stimulation for 2 hours in rats.
From: Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging
Representative image (from n = 6). Data are presented as means ± s.e.m, n = 6. When activated, the CrCEST signal of BAT increased, accompanied by the increase of water signal and the decrease of fat signal. Statistical analysis was performed using two-tailed paired Student’s t-tests, and each time point (10–120 min) was compared to 0 min (d), respectively. In Z-spectra, arrows were pointed to the water, fat, CrCEST, and APT peaks, respectively. Note that the area containing lung cavity is not shown due to sparse signal and artifacts.
