Extended Data Fig. 3: Comparison of thermogenic, lipolytic, insulin signaling, and cellular signaling proteins in aSAT between SED vs EX. | Nature Metabolism

Extended Data Fig. 3: Comparison of thermogenic, lipolytic, insulin signaling, and cellular signaling proteins in aSAT between SED vs EX.

From: Years of endurance exercise training remodel abdominal subcutaneous adipose tissue in adults with overweight or obesity

Extended Data Fig. 3

a) Protein abundance of UCP1 and PRDM16. b) Ratio of phosphorylated ATGL to total ATGL and phosphorylated HSL to total HSL. c) Protein abundance of phosphorylated AKT (Thr308 and Ser473), total AKT, and ratio of phosphorylated AKT to total AKT. P = 0.0132 for pAKTT308:AKT. d) Protein abundance of phosphorylated STAT3 (Tyr705), total STAT3, and ratio of phosphorylated STAT3 to total STAT3. e) Representative blot images from SDS-page Western blot analysis (UCP1, PRDM16) and JESS immunoblot analysis (pAKTT308, pAKTS473, AKT, pSTAT3Y705, STAT3) are presented separately. Sample sizes – SED: n = 16 and EX: n = 16. Data is expressed as mean ± SD.

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