Extended Data Fig. 4
From: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
a) Isotopologue fractional images for myristate (14:0), palmitate (16:0), palmitoleate (16:1), stearate (18:0) and oleate (18:1) in tumour tissue (tumour #1) from a mouse orthotopically implanted with GL261 IDH1 mutant glioma cells and fed with a liquid diet containing U-13C6-Glucose for 48 hours. Colours represent fraction of each isotopologue of the sum of all isotopologues for each fatty acid. b) Isotopologue fractional images for myristate (14:0), palmitate (16:0), palmitoleate (16:1), stearate (18:0) and oleate (18:1) in tumour tissue (tumour #2) from a mouse orthotopically implanted with GL261 glioma cells and fed with a liquid diet containing U-13C6-Glucose for 48 hours. Colours represent fraction of each isotopologue of the sum of the all isotopologues for each fatty acid.
