Extended Data Fig. 5: Additional metabolic cage parameters from NDUFS4-deficient mice treated with mitochondria or PBS.
From: Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome
(a) Body weight, and (b) rectal core body temperature of 7-week-old KO mice treated with PBS or 100 µg mitochondria 1-2 times per week. (c) Average energy expenditure (d) distance travelled, and (e) average respiratory exchange ratio (RER) over 3 hr after a 1 hr air equilibration period. Data are expressed as mean +/− SEM. All data points are unique biological replicates. For a, n = 11 PBS, n = 12 WT. For b, n = 11/group. For c-e, n = 15/group. Variation in n is due to mouse mortality. For c, Student’s t-test (two-sided). *P < 0.05. Data accompanies Fig. 3.
