Fig. 2: Contribution of modifiable participant characteristics or genetic factors to the variation in plasma abundances of the proteome.
From: Mapping biological influences on the human plasma proteome beyond the genome
a, UMAP projection of the matrix of variance explained for all protein targets. Proteins are coloured according to the class of the major contributor to their variation in plasma. GRS, genetic risk score. b, The total variance explained in the plasma abundance of each protein target by a range of participant characteristics and genetic factors, which are coloured according to higher order categories. We only show protein targets for which more than 10% of the variation in plasma was explained.
