Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Energy homeostasis

Cold-induced shivering for metabolic health

Nature Metabolism volume 6, pages 2218–2219 (2024)Cite this article

Subjects

This proof-of-concept study shows that 1 hour of cold exposure with shivering for 10 consecutive days improves glucose tolerance and other metabolic health outcomes in humans with overweight or obesity.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Cold exposure as a potential new tool for the treatment of metabolic disturbances associated with overweight and obesity.

References

  1. van Beek, S., Hashim, D., Bengtsson, T. & Hoeks, J. Int. J. Obes. 47, 338–347 (2023).

    Article  Google Scholar 

  2. Fernández-Verdejo, R., Marlatt, K. L., Ravussin, E. & Galgani, J. E. Mol. Aspects Med. 68, 82–89 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  3. World Obesity Federation. World Obesity Atlas. https://data.worldobesity.org/publications/?cat=19 (2023).

  4. Franz, M. J. et al. J. Am. Diet. Assoc. 107, 1755–1767 (2007).

    Article  PubMed  Google Scholar 

  5. Remie, C. M. E. et al. Nat. Commun. 12, 1516 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Hanssen, M. J. W. et al. Nat. Med. 21, 863–865 (2015).

    Article  CAS  PubMed  Google Scholar 

  7. Sellers, A. J. Nat. Metab. https://doi.org/10.1038/s42255-024-01172-y (2024).

    Article  PubMed  Google Scholar 

  8. Fernández-Verdejo, R. & Galgani, J. E. Sci. Rep. 12, 15925 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Shin, J.-A. et al. J. Diabetes Investig. 4, 334–343 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Guembe, M. J., Fernandez-Lazaro, C. I., Sayon-Orea, C., Toledo, E. & Moreno-Iribas, C. Cardiovasc. Diabetol. 19, 195 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Bull, F. C. et al. Br. J. Sports Med. 54, 1451–1462 (2020).

    Article  PubMed  Google Scholar 

  12. Beals, J. W. et al. Nat. Metab. 5, 1221–1235 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Perseghin, G. et al. N. Engl. J. Med. 335, 1357–1362 (1996).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA

    Rodrigo Fernández-Verdejo & Jose E. Galgani

  2. Centro de Fisiología del Ejercicio y Metabolismo, Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile

    Rodrigo Fernández-Verdejo

  3. Carrera de Nutrición y Dietética, Departamento de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile

    Jose E. Galgani

  4. Departamento de Nutrición, Diabetes y Metabolismo, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile

    Jose E. Galgani

Authors
  1. Rodrigo Fernández-Verdejo
    View author publications

    Search author on:PubMed Google Scholar

  2. Jose E. Galgani
    View author publications

    Search author on:PubMed Google Scholar

Corresponding author

Correspondence to Jose E. Galgani.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fernández-Verdejo, R., Galgani, J.E. Cold-induced shivering for metabolic health. Nat Metab 6, 2218–2219 (2024). https://doi.org/10.1038/s42255-024-01147-z

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/s42255-024-01147-z

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research