Extended Data Fig. 4: Significant enrichment of HD core transcription factors in iSPN mutant subpopulation. | Nature Metabolism

Extended Data Fig. 4: Significant enrichment of HD core transcription factors in iSPN mutant subpopulation.

From: Impaired striatal glutathione–ascorbate metabolism induces transient dopamine increase and motor dysfunction

Extended Data Fig. 4

a) Heatmap displaying the enrichment of 26 HD core TFs among different striatal purified populations at 3 M and 8 M. b, c) Smad3 gene expression levels in iSPN+ at 3 M (Control vs Mutant, p = 0.2) and 8 M (Control vs Mutant, p = 0.004 **). Values are means ± SEM; p statistic from unpaired, two-tailed Student’s t-test. Related to Fig. 3.

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