Extended Data Fig. 7: Effects of cold acclimation on the human skeletal muscle transcriptome, volcano plot (A), GSEA on GO-Biological Process terms (B), and KEGG taxonomy (C) of the comparison before and after cold acclimation. | Nature Metabolism

Extended Data Fig. 7: Effects of cold acclimation on the human skeletal muscle transcriptome, volcano plot (A), GSEA on GO-Biological Process terms (B), and KEGG taxonomy (C) of the comparison before and after cold acclimation.

From: Cold acclimation with shivering improves metabolic health in adults with overweight or obesity

Extended Data Fig. 7

The top 15 upregulated and downregulated gene sets in the 15 participants are shown. Differentially expressed genes were analysed by empirical Bayes moderation with two-sided paired t-tests, unadjusted for multiple comparisons, and defined as significantly changed when p ≤ 0.01 and log2FC > 1.5.

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