Extended Data Fig. 5: Evaluation of feimin levels in diabetic mice and humans. | Nature Metabolism

Extended Data Fig. 5: Evaluation of feimin levels in diabetic mice and humans.

From: A feeding-induced myokine modulates glucose homeostasis

Extended Data Fig. 5

a-b, Plasma insulin levels (a) and blood glucose levels (b) in male lean, diet-induced obese (DIO), ob/ob and db/db mice after overnight fasting (Fasted) or refeeding after overnight fasting (Refed). In refed mice, samples were collected 1 hr after the start of feeding. n = 6 mice. c-e, Plasma c-peptide levels (c), blood glucose levels (d) and ages (e) in normal and diabetic humans. Data are from 14 normal and 17 diabetic humans. Data are shown as mean ± s.e.m. Statistical comparisons were performed using an unpaired two-tailed Student’s t-test (e) or two-way ANOVA followed by Tukey’s test (a-d). All individual points and P values are shown.

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