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Early prediction of healthy ageing and age-related diseases using blood protein biomarkers

Nature Metabolism volume 7, pages 14–15 (2025)Cite this article

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Ageing is associated with proteomic changes in the blood. However, most research on the ageing blood proteome is cross-sectional in nature. Using a longitudinal analysis, we identified 86 ageing-related blood proteins and further revealed a subset of 22 protein biomarkers that, in combination, predict healthy ageing status and age-related cardiometabolic disease risk.

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Fig. 1: Ageing-related proteins identified by longitudinal proteome data.

References

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This is a summary of: Tang, J. et al. Longitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases. Nat. Metab. https://doi.org/10.1038/s42255-024-01185-7 (2025).

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Early prediction of healthy ageing and age-related diseases using blood protein biomarkers. Nat Metab 7, 14–15 (2025). https://doi.org/10.1038/s42255-024-01199-1

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